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KMID : 1149220040120010255
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Korean Journal of Oriental Medical Prescription
2004 Volume.12 No. 1 p.255 ~ p.262
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DPPH Radical Scavenging Effect of the Aerial Parts of Fagopyrum esculentum and Isolation of Bioactive Flavonoids
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Kim Sung-Ja
Kim Hyun-Joo
Park Jong-Cheol
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Abstract
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The inhibitory effect of the aerial parts of Fagopyrum esculentum on the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical was examined. The n-butanol fraction from the methanol extract of title plant showed stronger inhibitory effect than other fractions on DPPH radical. Two flavonoids were isolated from n-butanol fraction having the potent activity and elucidated as quercetin-3-O-α-L-rhamnoside and quercetin-3-O-rutinoside on the basis of spectral evidence. The IC50 values of these compounds on DPPH radical were 6.56 μM and 8.37 μM, respectively.
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KEYWORD
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Fagopyrum esculentum., 1, 1-diphenyl-2-picrylhydrazyl, radical scavenging effect, quercetin-3-O--L-rhamnoside, quercetin-3-O-rutinoside
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